KIR2DS5, the allele KIR2DS4*001 (Hoteit et al. 2014), and the combination of KIR2LD1−/KIR2DL2+/KIR2DL3− (Martínez-Sánchez et al. 2016), have been reported to be significantly more prevalent among MM patients compared to the healthy control population. This evidence concerns the gene KIR2DS4 and Miyoshi myopathy.