HIF1A and Peri-Implantitis: Peri-implantitis, despite its substantial impact on dental implants, remains a condition with ambiguous definitions and diverse etiologies, challenging our comprehension of its immunoinflammatory dynamics.(3,9,21) In this study, elevated levels of HIF1-α were observed in patients with peri-implantitis, unveiling a potential association with persistent inflammation-triggered hypoxia.