As expected, both AQP1 and AQP4 mRNAs were overexpressed in glioma samples (logFC = 1.42 x 10+14 and 1.02 x 10+14; P-value = 1.66E-40 and 8.82E-26, respectively) compared with the healthy brain samples (Table 1 and Figures 1A, B, 2). Here, AQP4 is linked to central nervous system cancer.