In NPC, METTL1 overexpression induces tumorigenesis, chemoresistance and epithelial–mesenchymal transition (EMT) by up-regulating the Wingless and Int-1/β-catenin (WNT/β-catenin) signaling pathway through increased WNT3A protein translation (79). This evidence concerns the gene METTL1 and nasopharyngeal carcinoma.