CD46 and autoimmune disease: This workup includes coagulation tests, quantification of ADAMTS-13 activity, investigation of autoimmune disorders (lupus anticoagulant, anticardiolipin antibodies, Beta-2-glycoprotein antibodies, antinuclear antibody) or metabolite deficiencies (vitamin B9, B12), exploration of complement levels (C3, C4, factor H, factor H autoantibody, factor I, factor B, and MCP/CD46 expression by flow cytometry), and, when available, measurement of sFLT1 and PlGF concentrations.