These findings suggest a possibility that various blood-circulating cytokines, especially IL-10, IL-8, IL-18, IL-1β, IFN-α2, IFN-γ, TNF-α, sIL-2Rα, sCD163, MIP-1δ, TECK, SCF, eotaxin-3, M-CSF, BCA-1, LIF, MIG, sTNF-R1, and sTNF-R2, would be dysregulated in COVID-19. The gene discussed is IL18; the disease is COVID-19.