Moreover, at an optimal cut-off value of 8.23 ng/ml, EZH2 could effectively distinguish bladder cancer patients from healthy individuals, with an AUC of 0.87 (95% CI: 0.526–0.963, p < 0.0001), a sensitivity of 81.31%, and a specificity of 78.42% (Figure 3). The gene discussed is EZH2; the disease is urinary bladder cancer.