For instance, a study utilized an HCC-targeting peptide (P47-P), an AFP epitope (AFP212-A2), and a functional domain of high mobility group nucleosome-binding protein 1 (N1ND-N) as exosomal anchor peptides to create a “trigger” DC sEV vaccine (DEXP&A2&N) (103). The gene discussed is AFP; the disease is hepatocellular carcinoma.