Subsequently, Kyoto encyclopedia of Genes and Genomes (KEGG) pathway analyses [28] revealed NF-κB, cytokine-cytokine receptor interaction, IL17 signaling pathway, Type I diabetes mellitus, MAPK signaling pathway and transcriptional misregulation in cancer as most altered pathways (Fig. 1a). The gene discussed is NFKB1; the disease is type 1 diabetes mellitus.