EMT is a pivotal process of HCC migration [23], unsurprisingly, RRP15 knockdown promoted the expression of epithelial marker E-cadherin, and diminished the mesenchymal markers N-cadherin and matrix metallopeptidase (MMP) 9 in the HCC cell lines (Fig. 2F). The gene discussed is RRP15; the disease is hepatocellular carcinoma.