GDF15 and hydrops fetalis: For HF rehospitalization over the entire follow-up period (Supplementary Table S17-18), reduction in GDF-15 levels from baseline to discharge was associated with decreased hazards and incidence of death in both univariate (CSHR 0.18, CI 0.08–0.41; SDHR 0.19, CI 0.09–0.45) and multivariate analyses (CSHR 0.20, CI 0.09–0.45; SDHR 0.20, CI 0.10–0.39).