Many studies reported that elevated levels of cytokines such as c-reactive protein, tumor necrosis factor alpha, interleukin 6, insulin like growth factor, interleukin 4, and interleukin 1 beta, had increased the danger of BC as the role of cytokines is to promote cell growth, proliferation, apoptosis prevention and metastasis and angiogenesis [24,61,63]. Here, CRP is linked to breast cancer.