FCGR3A and neoplasm: However, only a few examples utilizing B7-H3-binding moieties to redirect T or NK cells towards tumor cells can be found in the literature Among them, T cell engagers, CAR T cells, and a trispecific construct (TriKE) containing a B7-H3 scFv, an anti CD16 VHH, and rhIL15 as a proliferative signal to NK cells were described [6,13,41,42,43].