Cháirez Ramírez et al. stated that quercetin reduced the steady-state levels of p21-ras proteins in both colon cancer cell lines and primary colorectal tumors; these findings were confirmed by Western blot analysis and flow cytometry, which showed that p21-ras expression was reduced by approximately 50% of the control values. The gene discussed is HRAS; the disease is malignant colon neoplasm.