In another study, the methanol extract of CSR inhibits Aβ25–35 induced phosphorylation of dynamin-related protein 1 (Drp1) at Ser637 in HT22 cells and reduced the expression of Fission 1 Protein (Fis1) in H2O2 induced model for the treatment of Alzheimer’s disease (AD) [106]. Here, DNM1L is linked to early-onset autosomal dominant Alzheimer disease.