In terms of determining whether CD34+ cells are a promising source of cells for B-CNS-B restoration, human bone marrow CD34+ (hBM34+) cells were intravenously (iv) transplanted at three different doses of 5 × 104, 5 × 105, and 1 × 106 cells into a symptomatic G93A SOD1 murine model of ALS [47]. The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.