FN1 and chronic myelogenous leukemia, BCR-ABL1 positive: Our studies suggest that AGE-induced modification of extracellular matrix proteins increased CD40 expression in the diabetic retina since increased expression of CD40 in endothelial cells is associated with CML-expressing fibronectin, and fibronectin containing AGE-induced modification upregulates CD40 in endothelial cells.