CD14 and Cowden syndrome 1: Finally, the subset of intermediate (I) monocytes (CD14++, CD16+) significantly increased in the CS patients’ group (25.53 ± 3.7; p < 0.0001) and in the elderly (46–65 years: 15.63 ± 5.94; p ≤ 0.0001) compared to the healthy donors’ group (18–29 years: 6.39 ± 2.3) (Figure 5b).