Along with increased Ly6C+CCR2+ cells in skin wounds, we also observed elevated levels of circulating CCR2+CD115+Ly6C+ in the peripheral blood of HFD mice compared with ND controls on day 3 post-injury, suggesting that obesity increases production and/or mobilization of these cells in bone marrow. The gene discussed is CCR2; the disease is obesity due to melanocortin 4 receptor deficiency.