For example, Hsp90 inhibition by 17-AAG promoted AJ assembly in human corneal epithelial cells [74], whereas other Hsp90 inhibitors, geldanamycin and ganetespib, increased the expression and junctional accumulation of E-cadherin in human colonic adenocarcinoma cells [75,76]. The gene discussed is HSP90AB1; the disease is colon adenocarcinoma.