BRAF and melanoma: Accordingly, by taking advantage of previous proteomic data obtained in our laboratory by liquid chromatography–tandem mass spectrometry (LC-MS/MS) analysis [15,16], we identified a set of 98 proteins whose expression is downregulated at protein and Mrna levels in GALC overexpressing A2058 and A375 human melanoma cells (upGALC cells) harboring the BRAF(V600E) mutation.