GATA4 and familial dilated cardiomyopathy: At the validation step, we found that GATA4 showed significant downregulation (FC 0.43 ± 0.28) (p < 0.05), whereas FOG2/ZFPM2 was significantly upregulated (FC 3.57 ± 1.63) (p < 0.05) in DCM patients.