Then, those clusters were annotated into eight populations according to the expression of markers of well-known T cell types (Figure 5A,B, Table S12), including naïve T cells (Tns), antigen-presenting CD8+ T cells (APCs), proliferactive CD8+ T cells, effector memory T cells (Tems), cytotoxic CD8+ T cells (Tcs), T helper 17 cells (Th17s), terminally differentiated effector memory cells (TEMRAs), exhausted CD8+ T cells (Texs), and tumor regulatory CD4+ T cells (Tregs). This evidence concerns the gene CD8A and neoplasm.