However, our research goes a step further by uncovering a distinct relationship between macrophages and the C/EBPβ→NF-kB signaling pathway, as elucidated in Figure 2B. C/EBPβ, a transcription factor of immense physiological relevance, has been previously implicated in acute lung injuries, especially those triggered by immune complexes [32]. This evidence concerns the gene CEBPB and acute lung injury.