Dietary nitrate intake additionally inhibits the pro-inflammatory effects of acute exercise observed in MS patients, including the elevation of plasma concentrations of tumor necrosis factor α (TNFα), prostaglandin E1 (PGE1), prostaglandin E2 (PGE2), intercellular adhesion molecule 1 (ICAM1), and 16-hydroxy-palmitate (16-HPAL) [21]. The gene discussed is TNF; the disease is myeloid sarcoma.