Thus, these findings suggest that PRMT1 plays a key role in GSC growth by upregulating STAT3-mediated downstream GBM stemness regulators and that the PRMT1 inhibitor furamidine, either alone or in combination with the CaMKIIγ inhibitor berbamine, may be a novel anticancer agent to eliminate GSCs. The gene discussed is PRMT1; the disease is glioblastoma.