LCN2 and oculocutaneous albinism type 1: In the RNAi experiments, renal IR significantly increased all renal injury markers (BUN, Lcn-2 concentrations and Lcn-2 mRNA) and morphological damage (ATN score) at 24 h after severe (30 min) and mild (15 min) ischemia (Figure 4a–e), similarly to that of the enzyme inhibition experiment.