Similarly, lncSNHG14, identified to be overexpressed in DLBCLs, was reported to be an miRNA sponge of the 3p strand of MIR5590 that upregulated ZEB1, a protein that promotes cell proliferation and the EMT and a transcription factor for SNHG14 and PD-L1, a checkpoint protein which impairs CD8+ T-cells’ anti-tumor immune activity [229]. The gene discussed is CD8A; the disease is neoplasm.