KCNQ2 and developmental and epileptic encephalopathy: Initially linked to self-limited neonatal epilepsy (SeLNE) [5,6], de novo missense KCNQ2 mutations have also been associated with a more severe phenotype referred to as developmental and epileptic encephalopathy (KCNQ2-DEE) [7,8,9,10,11,12,13].