EIF2AK3 and fibromyalgia: Furthermore, cold stress increased pERK, pP38, and pJNK levels as well as those of pCREB and pNF-kB in the SSC of the fibromyalgia group (Figure 3B, * p < 0.05, n = 6), an effect reversed by EPA treatment (Figure 3B, # p < 0.05, n = 6).