Finally, we demonstrate that MtbCoM or LPSCoM induced the expression of CXCL8, IL-13, and IL-6 from neutrophils, which are cytokines all known to contribute to an exacerbation of human lung pathologies, including TB and ARDS, which can result from chronic pneumonia [43,44,45,46]. Here, CXCL8 is linked to tuberculosis.