PFN1 and tuberculosis: The five identified TB-related proteins (alpha-1-antichymotrysin, plasminogen, macrophage-capping protein, f-actin-capping protein subunit beta, and profilin-1) identified by label-free liquid chromatography with tandem mass spectrometry, using saliva from 22 adults with symptoms of TB, with an AUC greater than 0.8, play a crucial role in enzyme regulation, immune system activation, and inflammation [131].