All coDASG_DEGs in pathways such as Porphyrin metabolism, Rheumatoid arthritis, Cytosolic DNA-sensing pathway, and Autophagy—other showed significant downregulation in Eastern pigs involving ATG4A, ATP6V1E1, BLVRB, CCL5, FECH, GABARAP, HMBS, IL15, IL18, IRF7, and UROS (Figure 2C). Here, ATP6V1E1 is linked to rheumatoid arthritis.