High basal levels of TNFR2 were previously associated with lower relapse-free survival in CM patients [17], and miR-1271 was previously associated with the inhibition of cell growth in lung cancer through mTor suppression [55], colorectal cancer by downregulating methaderin/Wnt signaling [56], and prostate cancer by the inhibition of the MAPK pathway [57]. This evidence concerns the gene TNFRSF1B and Familial prostate cancer.