We previously observed that the expression of NDRG2 was low in many types of solid cancers, including SAS (oral squamous cell carcinoma) and U2OS (osteosarcoma), and cell proliferation was significantly suppressed by silencing PRMT5 expression with the degradation of AKT and NEMO proteins [10]. Here, NDRG2 is linked to oral cavity squamous cell carcinoma.