Tillack et al. investigated the role of the rare G/G variant rs11209026 (p.Arg381Gln) of IL23R in determining the onset of skin psoriasiform lesions in patients receiving anti-TNFα; although the association was not statistically significant, all of the patients with severe psoriasiform skin lesions and/or anti-TNF-induced alopecia switched to ustekinumab were carriers of this variant [38]. The gene discussed is TNF; the disease is neoplasm.