SLC26A4 and hearing loss disorder: Pendrin-coding SLC26A4 is a causative gene for Pendred syndrome (PDS, OMIM 274600), which is one of the most common types of syndromic hearing loss with enlarged vestibular aqueduct (EVA) and goiter, as well as nonsyndromic hearing loss (DNFB4, OMIM600791) [7,8].