DNA hypermethylation in the promoters of CXCL14, CXCL5, GATA3, IL17C, and IL4R and hypomethylation in the promoters of CCL25, IL13, IL12B, CXCL5, IL4R, IL17A, and IL17RA are associated with the onset or aggravation of ulcerative colitis [149]. This evidence concerns the gene CXCL5 and ulcerative colitis.