EZH2 and diffuse large B-cell lymphoma: On the other hand, the dual inhibition of EZH2 and Bcl-2 (by TAZ and Venetoclax, respectively) exerted a synergistic effect in mediating the apoptotic response in diffuse large B-cell lymphoma, while in the same context, TAZ was shown to induce cell cycle arrest and apoptosis against lymphoma cells in preclinical models [28,29].