An important compound derived from Chamaecyparis obtusa in the treatment of atopic dermatitis (AD) is elemol, which decreased IgE serum levels, infiltration of mast cells into the hypodermis and dermis, and expression of TNF-α, IκBα, IL-6 and IL-1β in the skin of the 2,4-dinitrochlorobenzene-induced animal models of atopic dermatitis. This evidence concerns the gene IGHE and Alzheimer disease.