CDH2 and breast carcinoma: As a result of further experiments, the authors observed that this extract inhibited cell migration in MDA-MB-231 and reduced the levels of epithelial-mesenchymal transition (EMT) marker proteins, such as N-cadherin, fibronectin and TWIST, and the levels of CDH2, FN1, TWIST1, MMP2 and MMP9 genes, which suggested that it could inhibit breast cancer metastasis by suppressing various EMT-related genes.