Since it was reported that autophagy is induced by multiple anticancer agents (specially mTOR inhibitors) as a tumor-survival-promoting mechanism [40,41], we also assessed whether the mTOR inhibition induced by M36 treatment would affect the activation/phosphorylation status of serine/threonine kinase Unc-51- like kinase-1 (ULK1), which is crucial in inducing autophagy/mitophagy. This evidence concerns the gene ULK1 and neoplasm.