JAK2 and myocardial ischemia: Another study using the mouse models of myocardial ischemia–reperfusion showed that cilostazol treatment attenuated multiple inflammatory markers through the activation of the peroxisome proliferator-activated receptor-γ (PPARγ), Janus kinase 2 (JAK2), and the signal transducer and activator of transcription 3 (STAT3) pathways [78].