LGI1 and acrodermatitis enteropathica: To address the question of whether a specific T cell response to the LGI1 antigen with subsequent cytokine release occurs in LGI1 ab-mediated AE, herein, we evaluated the effect of recombinant LGI1 on the proliferation and cytokine production of PBMCs from 4 patients with LGI1 ab-mediated LE and 10 healthy controls in vitro.