BUB1B-PAK6 and ITGA8 in muscle-related signaling pathways showed increased expressions in polyp tissues, while COX6A2, TUBA3E, KCNMB2, ITGA10, ACTC1, MYL19, ACTA2, PPP1R12B, DES, PLN, SLC8A2, KVNMB1, and ACTG2 showed decreased expressions in polyp tissues (Figure 4b and Figure S5, and Table S3). The gene discussed is ACTG2; the disease is polyp.