VDR and melanoma: In RPMI7951 melanoma cells treated simultaneously with each of our tested FGFR inhibitors and 1,25(OH)2D3, but not for a monotreatment, we observed an increase in the mRNA level for VDR (Figure 6A, p < 0.01 for CPL304110 and p < 0.01 for AZD4547).