It is worth pointing out that SUV4-20H2 exerts the aforementioned effects through transcriptional regulation of MET-associated transcriptional factors, namely forkhead box A1 (FOXA.1) and Ovo-like transcriptional repressor 1 and 2 (OVOL1/2) in pancreatic cancer, which in turn have the ability to activate different downstream signaling pathways. The gene discussed is FOXA1; the disease is familial pancreatic carcinoma.