CD4 and fatty liver disease: The dysregulated gut immune barrier was showed by significantly increased values of CD4+IL-2+ pro-inflammatory patterns in CII and AII tissue samples recovered from hepatic steatosis patients reported to controls (CII: 37.15 ± 5.36; AII: 34.57 ± 3.81 vs. C: 13.13 ± 4.04, p < 0.05, Figure 1A,D,G,K,M and Figure 2C).