Late apoptosis represents the chronic response to injury induction by gut immune barrier dysfunction, oxidative stress, and the liver-dysregulated barrier, being observed in duodenal tissue samples with chronic inflammation recovered from patients with hepatic cirrhosis and steatosis, compared with controls, using Annexin V-FITC/PI dual stain (Figure 10H,J). The gene discussed is ANXA5; the disease is Cirrhosis.