Hung et al. described cases of ARVC diagnosed using these methods; they found a decrease in the expression of αT-catenin and plakophilin-2 (PKP-2) as a consequence of a CTNNA3 gene mutation, although it is not commonly involved in the pathology onset [24]. This evidence concerns the gene PKP2 and arrhythmogenic right ventricular cardiomyopathy.