On the other hand, miR-101-3p also inhibits GB proliferation, migration, and invasion in vitro as well as tumor growth in vivo, at least in part, by directly downregulating SRY-box transcription factor 9 (SOX9) TF, which, in turn, promotes the activity of the AKT, WNT, and BML1 pathways [114]. This evidence concerns the gene SOX9 and neoplasm.