MKI67 and neoplasm: Based on the ROC curve, cut-off points were provided for other determinants as follows: for Ki-67 expression, the cut-off value was 15% with 54.1% specificity and 77.8% sensitivity (AUC = 0.702, p = 0.0220); the cut-off value for pre-treatment AOPP concentration was 9.37 μM with 75.4% specificity and 66.7% sensitivity (AUC = 0.726, p = 0.0128); for the tumour diameter, the cut-off point was 2.1 cm with 70.5% specificity and 77.8% sensitivity (AUC = 0.773, p = 0.0005).